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Beyond 12 Months: Long-term Maintenance Beyond 12 months, the focus shifts from active weight loss to long-term maintenance and health optimisation

Our findings suggest we can begin identifying which patients are most likely to respond to specific therapies rather than treating obesity as a single disease. The team studied 483 adults with obesity, identifying three different biological types

Objective measures like rising fasting blood glucose levels are the most reliable indicators

Over time, that overstimulation can lead to tumor formation

Patients receiving sitagliptin with metformin immediate-release and insulin had significant improvements in A1C, FPG and 2-hour PPG compared to patients receiving placebo with metformin immediate-release and insulin (Table 13)