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Add antiinflammatory effects in fat tissue and subtle changes to the gut microbiome, and you have a plausible multipathway explanation for why some people experience berberine belly fat reduction in trials and practice

Pain is usually in the upper belly and might go to your back

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Chen, Y., Lin, Y

Form and Analytical Testing Powder (lyophilized sterile powder or free base crystals), 99% purity (HPLC), identity confirmed by mass spectrometry and chiral analysis, endotoxin 1000 mg/mL in water, appearance: white crystalline powder, storage 28C protected from light and moisture, reconstitution with sterile or bacteriostatic water under aseptic conditions, stability: 2436 months sealed refrigerated, 12 weeks reconstituted at 28C (avoid multiple freeze-thaw)