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Following the lead-in period, eligible patients with A1C 7% to 10% were randomized to either 2.5 mg or 5 mg of saxagliptin add-on to 7.5 mg glyburide or to placebo plus a 10 mg total daily dose of glyburide

Assessments were based on changes in patients body mass index (BMI), total cholesterol, HDL-C, LDL-C, triglycerides, apolipoprotein B, lipoprotein(a), and hemoglobin A1c (HbA1c) over a 2-year follow-up period in patients who persisted in taking their medication versus those who discontinued use

Browse all Blood Testing & Biomarkers education Medical and Editorial Standards Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims

Promotes glutathione synthesis

Conuel EJ, Chieng HC, Fantauzzi J, Pokhrel K, Goldman C, Smith TC, Tiwari A, Chopra A, Judson MA