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Aside from individuals using SGLT2 inhibitors, euglycemic DKA is also observed during pregnancy, among those with impaired gluconeogenesis owing to alcohol abuse or impaired liver function, and thus requires caution [824]

Purity Assessment: Utilization of validated chromatographic techniques, such as high-performance liquid chromatography (HPLC), to ensure research-grade quality

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A systematic review and meta-analysis published in eClinicalMedicine found a clear metabolic rebound after discontinuation and the STEP-1 extension trial showed participants regained roughly two-thirds of the weight they had lost within a year of stopping semaglutide

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