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The two papers that originally established this mechanism have been retracted

For instance, Hu et al

5 Conclusion This systematic review and meta-analysis indicate that sublingual and oral vitamin B12 administration provide efficacy comparable to intramuscular injection in improving serum cobalamin levels and reducing hyperhomocysteinaemia

Extensive research confirms its ability to stimulate hair growth

Scientists investigating growth factor signaling and cellular proliferation have recognized IGF-DES as a valuable research tool for studying IGF receptor activation without the confounding effects of IGFBP sequestration