"Healthy dietary and lifestyle practices should remain the foundation for obesity treatment and management, with medications such as GLP-1 receptor agonists used as adjuncts." "Such practices not only help prevent excess weight gain but can also lead to numerous health benefits that go beyond weight control," he concludes
( b-e ) Body weight ( b ), circulating glucose ( c ), BHB ( d ) and insulin ( e ) in male and female mice fed CD, HFD, or KD over the experimental timeline
doi:10.1016/s0197-0186(03)00133-5 Bains VK, Bains R
Blood glutathione and cysteine changes in cardiovascular disease
24 NICE recommends semaglutide for weight management for up to 2 years, and CDA-AMCs reimbursement review similarly assesses semaglutide within an HTA framework focused on a single, continuous course of treatment strategy rather than repeated on/off cycles