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Moreover, microbial transplantation studies in germ-free mice with human commensals containing a functional (but not a deletion mutant) microbial cutC gene (responsible for cholineTMA transformation) (23) and genetic manipulation (both gain of function and loss of function) of host hepatic flavin monooxygenase 3 have been shown to modulate host TMAO levels, platelet responsiveness, and thrombosis potential in vivo (24)

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Pioglitazone therapy in progressive differentiated thyroid carcinoma

Int J Mol Sci 11:268287 Canesi L, Viarengo A (1997) Age-related differences in glutathione metabolism in mussel tissues ( Mytilus edulis L)

Gene Expression Modulation (the "4,192 genes" data point) The Broad Institute Connectivity Map analysis is the single most-cited modern data point on GHK