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In a randomized, double-blind, placebo-controlled trial, patients with preserved small nerve fiber function as defined by QST had a statistically and clinically significant improvement in pain

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It is expected that when Retatrutide is FDA-approved and made available by Lilly (trade name has not yet been announced), it will be quite expensive and possibly not covered by pharmacy benefit insurance plans, as is often the case with Semaglutide and Tirzepatide

Anti-inflammatory activity was further evaluated using the carrageenan-induced peritonitis model in mice