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Seek medical attention if you experience extreme thirst with massive urine output (possible diabetic emergency), dark urine despite adequate fluid intake, pain or burning during urination, blood in urine, sudden decrease in urine output, or if increased urination persists beyond 12 weeks without improvement

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PMID: 28132746, DOI: 10.1016/j.jacc.2016.11.004

A separate meta-analysis published in Cureus (October 2025) covering studies from January 2010 to October 2024 found that weight regain after GLP-1 discontinuation is a documented clinical challenge driven by the body's own hormonal responses - hunger signals return, energy expenditure adapts

Frequently asked questions Phaze is purpose-built for GLP-1 users on medications like Ozempic, Mounjaro, Wegovy, and Zepbound