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Methods Trial Design Both trials were randomised, open-label, parallel-group, single-centre (Parexel, Berlin, Germany) trials (Fig
Subgroup analyses showed significant difference in FPG reduction between the exenatide group (1.02 mmol/L, 1.38 to 0.67, I 2 = 0%, P = 0.49) and sitagliptin group, and a significant reduction in liraglutide group compared to sitagliptin groups (1.14 mmol/L, 1.40 to 0.88, I 2 = 0%, P = 0.56) as well
However, some individuals may need to speak with their healthcare providers to ensure that symptoms are manageable or to adjust their dosage if diarrhea persists or becomes severe
However, subsequent research revealed that HGF and its receptor c-Met are widely expressed in the brain, particularly in the hippocampus, cortex, and cerebellum
They are being highlighted for their potential to mimic the effects of GLP-1 medications like Ozempic and Wegovy, primarily used for type 2 diabetes and weight loss
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