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A 2025 Phase III randomized controlled trial, HARVEST, confirmed that more intensive antibiotic treatment higher-dose rifampicin also fails to move the needle: no survival benefit was found, per the New England Journal of Medicine publication of the HARVEST trial

Percent of patients clustered together using RNA and protein who are also clustered together using RNA or protein alone

In contrast, in some other Chinese provinces (e.g., Enshi), Se intake was very high (2.1446.69 mg/day), and endemic selenosis outbreaks appeared (56, 73)