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Wilmes A, Bielow C, Ranninger C et al (2015) Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics

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The work shows that LXA4 acts via the ESR2/LPAR3/Nrf2 axis to provide its anti-inflammatory and anti-ferroptotic actions in vitro cell co-culture and in vivo rat models, offering a novel therapeutic target for the intervention of KOA [110]

Samples from the basolateral side are taken at different time points during ~2 h ( The short circuit current (I sc ) is also often calculated during electrophysiological measurements and refers to the amount of current needed to force the PD to 0 mV

Neurons and glial cells operate in a constant state of managing oxidative products, therefore making the CNS inherently vulnerable to redox dysregulation