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doi: 10.3389/fimmu.2021.638841 108 Groth CHXWeberRFlemingVAltevogtPUtikalJUmanskyV

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The way HP survives these stressful environmental changes is through its production of the powerful antioxidant astaxanthin

Collectively, it may be hypothesized that obesity induces feedback inhibition of pituitary GH secretion by increasing non-fasting serum FFA levels and the associated insulin resistance that causes compensatory intra-portal hyperinsulinemia and IGFBP-1 suppression, with the net result being low GH and normal IGF-I levels