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Why It Matters Patients with true resistant hypertension are at higher risk of: Hypertension-mediated organ damage (HMOD) Chronic kidney disease progression Cardiovascular events (MI, stroke) Increased mortality Unlike pseudo-resistance, true resistance often requires specialized evaluation, including screening for secondary causes such as primary aldosteronism, renovascular disease, or obstructive sleep apnea

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NIRS captures changes in regional cerebral oxyhemoglobin concentration every 0.1 s