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This debate emphasizes the need for validation of leptin-CRP interaction in humans, and careful experimental technique in this pursuit, particularly as species specificity limits the utility of rodent models (60)

[PMC free article: PMC3869438] [PubMed: 23581713] 374

Cells were seeded at 50,000 per well in 6-well plates and at 10,400 per well in 24-well plates

These advances highlight the versatility and therapeutic potential of GLP-1R-targeted nanomedicines to comprehensively address the multifactorial pathology of PD