glp 1 rhabdomyolysis The Interplay Between GLP-1-Based Therapies, the Gut Microbiome, and MASLD/MASH in Type 2 Diabetes Mellitus: A Narrative Review GLP-1R Agonists for Weight Loss

GLP-1R is expressed on cocaine- and amphetamine-regulated transcript (CART)/proopiomelanocortin (POMC) neurons in the hypothalamus, which regulate satiety and termination of meals [40]

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Clinical trials have shown that discontinuing treatment typically results in gradual weight regain and worsening glycemic control, underscoring that these are chronic disease management tools rather than short-term interventions