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Its a peptide too large and too polar to cross the gut, and it gets destroyed by enzymes before itd get the chance

Nonlethal inhibition of gut microbial trimethylamine N-oxide production improves cardiac function and remodeling in a murine model of heart failure

Journal of Psychiatric Practice

MCT Wellness might be the solution

Supplementation of vitamin B12 COMPOSITION Cyanocobalamin (Vitamin B12) 1mg/mL ACTIONS Supplementation of Vitamin B12 INDICATIONS Vitamin B12 supplement for the treatment of macrocytic anaemia in horses and dogs DOSAGE AND ADMINISTRATION Administer intramuscularly twice weekly or as directed by a veterinary surgeon