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Thus, precise and quantitative biomarkers for preclinical and clinical in vivo assessment of engagement at the individual receptors would assist the drug candidate selection and development process

Really cool work

Bhaskaran K, Douglas I, Forbes H, dos-Santos-Silva I, Leon DA, Smeeth L

Proponents of this method argue that the peptide is stable enough to travel and act on receptors wherever they may be

Nat Methods 16:12891296 Lee SH, Chaves MM, Kamenyeva O, Gazzinelli-Guimaraes PH, Kang B, Pessenda G, Passelli K, Tacchini-Cottier F, Kabat J, Jacobsen EA et al (2020) M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis