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According to Ohkawa, et al

The most common cause of gout (about 90% of cases) is the inability to excrete enough uric acid in the urine

The impressive 24.8% concentration means you're getting a really effective dose, which explains why I've seen such noticeable improvements in my skin's luminosity and overall clarity

For example, in the study we cited where berberine went up against metformin, 35% of subjects had significant gastrointestinal upset when taking the 1,500 mg/day dose (three capsules worth)

The long-term (74 weeks) treatment also induced lipogenesis (increased expression of fatty acid synthase [FAS]), in contrast to decreased FAS expression in rat livers after the short-term treatment