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The approach is based on general pharmacological principles (gradual receptor adaptation improves tolerability) and clinical observation

Lower inflammation means better cellular communication and improved tissue repair two critical ingredients for regenerative success

When microglia are exposed to UCB, they produce TNF, IL-1, and IL-6, as well as glutamate

It's important to contextualize this concern: No published study has shown BPC-157 causing or promoting tumor growth The body already produces BPC-157-related compounds naturally in gastric juice Many foods and supplements (such as curcumin and certain vitamins) also promote angiogenesis without being considered cancer risks The concern remains theoretical, not evidence-based, but it warrants continued research Out of an abundance of caution, we recommend that individuals with active malignancies consult their oncologist before using BPC-157