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At the same time, in low concentration, they serve as secondary messengers during signalling cascades and regulate various metabolic responses in plants

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Overexpression of FZD7 activates the carcinogenic factor Tp63, drives the up-regulation of GPX4, and protects cells from chemotherapy-induced oxidative stress

Because of this short half-life, clinical experts often recommend splitting the daily dose (e.g., taking half in the morning and half in the evening) to maintain steady, round-the-clock antioxidant levels in the bloodstream

The cytoprotective compounds were subsequently demonstrated to be effective radical-trapping antioxidants, which protect lipids from autoxidation, the autocatalytic radical chain reaction that produces lipid hydroperoxides