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in 2019 showed that the nuclear translocation of phosphorylated P65, the inhibition of IB kinase (IKK) within the NF-B signaling pathway, and phosphorylation of ERK, JNK, and P38 MAPK (i.e., activation of the MAPK signaling pathway) can control the production of IgE and IL-4 and inhibit inflammatory mediators in asthma