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Commercially available 1-stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine, 1-stearoyl-2-15(S)-HETE-sn-glycero-3-phospho-ethanolamine (Cayman Chemicals), 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphoethano-lamine, 1,2-dioleoyl-sn-glycero-3-phospho-ethanolamine, 1-palmitoyl-2-(5-oxo-valeroyl)-sn-glycero-3-phosphocholine, 1-palmitoyl-2-(9-oxo-nonanoyl)-sn-glycero-3-phosphocholine (Avanti Polar Lipids) were used as reference standards

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However, excessive or impaired angiogenesis, even if initially compensatory, can become pathological, exacerbating neurodegenerative processes by increasing vascular instability and inflammation (Sweeney et al