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WARNINGS Patients with early Lebers disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

Chung, Applied materials science: Applications of engineering materials in structural, electronics, thermal, and other industries (CRC, 2001)

Eventually, they get so short that cells cant divide and make new cells properly anymore

Nat Rev Neurosci 10(7):508523

This has motivated therapeutic strategies that modulate proteostasis to recalibrate immune responses rather than solely suppress downstream inflammation

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