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Interestingly, they also assessed 1.5% CGN in drinking water in Guinea pigs for 40 days and found no GI lesions, no increase in prostaglandin E2, and a decrease in leukotriene B4

A Glimmer of Hope for Adults with Comorbid Insomnia In a surprising contrast to the findings on primary insomnia, the review identified one study that looked at medically ill adults with comorbid insomnia

Consistency is key, as the benefits of these supplements are cumulative over time