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In Phase 1 studies, survodutide was generally well tolerated, with no significant safety or tolerability issues observed in either healthy individuals with overweight or obesity [87, 88]

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Clinical data shows patients who discontinue without tapering regain an average of 25 pounds per week in the first month alone

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Koehler et al., 2015) (Table 1)

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GLP-1RA promotes brown adipogenesis of C3H10T1/2 mesenchymal stem cells via the PI3K-AKT-mTOR signaling pathway

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