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Timeline for Complete GLP-1 Clearance from Your Body Most patients achieve near-complete elimination of GLP-1 medications within 4 to 5 half-lives, which translates to roughly 28 to 35 days for semaglutide and 20 to 25 days for tirzepatide

TIER 0 (20mg total) $235 total for 10 week supply Monthly cost breakdown: $94 Recommended if using low (or micro) doses of 2mg/week or less TIER 1 (40mg total) $325 total for 8-10 week supply Monthly cost breakdown: $130-$162 based on weekly dose Recommended if new to treatment or for those on 2-5mg/week TIER 2 (60mg total) $340 total for 8-10 week supply Monthly cost breakdown: $136-$170 based on weekly dose Recommended for those on 6-7mg/week TIER 3 (90mg total) $380 total for 9-10 week supply Monthly cost breakdown: $152-$168 based on weekly dose Recommended for those on 8-10mg/week TIER 4 (120mg total) $395 total for 8-10 week supply Monthly cost breakdown: $158-$197 based on weekly dose Recommended for those on 11mg/week and up Boudreaux Pharmacy - Tirzepatide/Glycine Injection (NEW) Up to 90 days BUD

Subsequent appointments every 812 weeks can monitor progress and adjust treatment as needed

For deferrals related to dehydration or acute illness, you can typically attempt donation once you have fully recovered and have been symptom-free for at least 24-48 hours, though specific timeframes may vary by donation center

Sci Signal (2010) 3(112):re3