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In addition, STAT3 can regulate the membrane expression of a variety of mitochondrial and cell membrane-related genes, thereby affecting mitochondrial function and cell membrane integrity, thereby affecting cell survival and death

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In order to maintain low levels of reactive oxygen species (ROS), ascorbate peroxidase (APX) and GPX convert hydrogen peroxide to water in the ascorbate (AsA)-glutathione (GSH) cycle and oxidized glutathione (GSSG)-GSH cycle, respectively [8, 9]

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