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Abstract With age the apolipoprotein E ( APOE ) E4 allele (involved in lipid homeostasis) is associated with perturbation of bioenergetics pathways in Alzheimers disease (AD)

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[DOI] [PubMed] [Google Scholar] 153.Salama A, Elgohary R

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Notably, efficient fatty acid metabolism, particularly beta-oxidation for energy production, requires adequate levels of L-carnitine, which acts as an essential cofactor for transporting long-chain fatty acids into the mitochondria