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Additionally, metformin has been shown to be well-tolerated in patients with active cancer, making our outcomes more meaningful by comparison. In a subanalysis, researchers matched 1,620 adults with type 2 diabetes on metformin who were newly starting a GLP-1 with those on metformin who were newly starting insulin up to 3 months before or after initiating systemic cancer therapy

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Whereas the general population unaffected by lipedema gain weight more in the belly or abdomen and less on their legs and arms, lipedema patients gain the weight in an inverse fashion, with more growth on their legs and/or arms and less on their abdomen

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Carnitine depletion has several adverse effects