Types of GLP-1 medications GLP-1 therapies are available in several different forms: Once-weekly injections Daily oral or injectable options Combination therapy with insulins Xultophy (insulin degludec + liraglutide) IcoSema (weekly insulin Icodec + Semaglutide) Soliqua (insulin glargine and lixisenatide) How the main GLP-1 drugs compare While all GLP-1 medications work through similar mechanisms, they differ in strength, dosing frequency, weight loss effects, and side-effect profiles
Four datapoints were excluded for one cage in vehicle group due to food spillage on day 11-14
In a large phase 3 obesity trial (ACHIEVE-1), orforglipron at daily doses of 3, 12 and 36 mg caused approximately: Diarrhoea: 1926% of participants (vs 9% on placebo) Nausea: 1318% (vs 2% on placebo) Constipation: 817% (vs 4% on placebo) Vomiting: 514% (vs 1% on placebo) Across multiple studies, 617% of people stopped treatment because of side effects, mostly gut-related symptoms
Dissolve the powder After adding the water, do not shake the vial
If youre a nutritionist and havent yet encountered GLP-1 medications in your pediatric practice, you soon will
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