The claim that "over 75% of patients achieve significant pain relief without surgery" with peptide therapy comes from clinical observations, not controlled trials
Microbiome: effects of ageing and diet
I took a screenshot to show you but theres no place to add that in this comment space.
DeLong) The effects of chronic stimulation of the cerebellar cortex as a treatment for movement disorders were explored before, by a small number of investigators, in the setting of cerebral palsy (CP) with spasticity and dystonia (or athetosis, as it was commonly called [111, 125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144]) and epilepsy
It also reinforces a point I raised previously: that the clinical conversation at the point of prescribing needs to account for the individual patients baseline muscle mass and age-related risk profile, not simply their weight and BMI