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Completed Phase II and III clinical trials have indicated that the agent has a nonoverlapping toxicity profile and synergistic effects with carboplatin, paclitaxel, and anthracycline, has no cross-drug resistance and is well tolerated, with patients mostly reporting fatigue and nausea

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doi: 10.1152/japplphysiol.00164.2004 [DOI] [PubMed] [Google Scholar] 48

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