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[20] [21] Proton pump inhibitors (PPIs) such as omeprazole can reduce B12 absorption and may cause digestive upset

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[34] showed that treatment with the GLP-1 RAs exenatide and liraglutide reduced both systolic and diastolic BP by 1 to 5 mm Hg in patients with T2D, compared with some other anti-diabetic drugs, including insulin, glimepiride, and placebo

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While likely safer than long-acting systemic analogs, IGF-1 DES is not without risks

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