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9 The enigmatic interplay: macrophages and ferroptosis in disease Ferroptosis, a distinct form of regulated cell death, holds significant importance in the pathology of various diseases, particularly in oncology, as illustrated in Figure 9

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By contrast, CIBB treatment in the CI-M group significantly reduced the percentage of M1 macrophages (31.81% in the CI-M group) and increased the percentage of M2 macrophages (26.18% in the CI-M group) close to that in the control group

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Schchinger V, Britten MB, Zeiher AM