16 , 41 , 42 However, these findings should be considered hypothesis-generating and warrant confirmation through dedicated head-to-head RCTs comparing the safety and efficacy profiles of different GLP-1 RAs
Serious but less common risks include pancreatitis, gallbladder problems, dehydration from severe vomiting or diarrhea, worsening diabetic retinopathy in some patients with existing eye disease, and allergic reactions
In this Phase I study, the highest dose of MariTide resulted in a body weight loss of 14.5% by day 85, compared to the placebo group, who gained 1.5% body weight
For readers exploring the diabetes-prevention angle of this same compound, the companion analysis of whether cagrilintide can prevent diabetes in high-risk patients examines the glycemic data in more depth
Plan for follow-ups and ongoing support