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If constipation persists beyond 12 weeks despite implementing all strategies, consider the pelvic floor evaluation discussed above and consult your healthcare provider about potential dose adjustments

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Pak K.Y., Cutri R.M., Nadeem W., Kothari D., Wong Y.T., Wu A.W., Miller M.E

Stop using GLP-1 and call your healthcare provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting

Therefore, anyone using GLP-1s should require oversight of nutrition: adequate protein, micronutrients, healthy fats, fiber, and perhaps supplementation/support as needed

166 The main action of ghrelin is to induce hunger by acting on hypothalamic brain cells expressing the ghrelin receptor