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Another enigmatic G protein is -gustducin, a key element in sweet-taste transduction pathways downstream of the heterodimer formed between the GPCRs Tas1R2 (T1R2) and Tas1R3 (T1R3)

Along with a lack of robust studies into these peptides, recent analysis of some of the products , externalsuggests that 8% may be contaminated with bacterial endotoxins

This represents a huge population (in the US alone) for companies to consider as a lucrative opportunity for a type of drug that only 3-4 years ago was not even in the picture - for the treatment of overweight or obesity, which was burdened with a huge taboo

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