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TNF can promote insulin resistance in adipocytes (177), and FAs can activate JNK to promote the additional release of pro-inflammatory cytokines from macrophages (178) and adipocytes (179), inciting a vicious cycle

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Brand names differ by indication: Wegovy and Zepbound are FDA-approved for obesity

As the frozen meal segment continues to evolve, the introduction of high-protein options like the Max Pro pizzas may influence market dynamics, potentially attracting a broader customer base interested in healthier meal solutions

The international team that runs the trial includes Professor Deanfield