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This complex can dysregulate transcription factors involved in cell cycle regulation, such as activator protein 1 (AP-1), thereby promoting abnormal cellular proliferation, migratory behaviour, and metastasis, and driving AP-1-dependent transcriptional programs essential for cell cycle control in several cancer cell lines [23]

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Exenatide treatment caused a further drop in the fasting BGL in all four meal schedule conditions

More recent research has explored AOD9604 for other potential applications beyond obesity, including osteoarthritis treatment based on observations of cartilage regeneration properties in preclinical models, though clinical validation of these additional indications is limited