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Dose escalation temporarily disrupts electrolyte balance, slows gastric emptying more dramatically, and accelerates metabolic shifts
Iwan Steffan's mum died when he was 13 from skin cancer
In homeostatic conditions, the association of pericytes and ECs decreases paracellular migration of peripheral immune cells and other inflammatory factors and supports the structure and maintenance of the BBB (Daneman and Prat, 2015
Fortunately, GLP1 medications are now FDA-indicated for multiple indications beyond weight management and diabetes, including: Major cardiovascular event (heart attack and/or stroke) risk reduction in adults with cardiovascular disease and overweight or obesity Metabolic dysfunctionassociated steatohepatitis (MASH) Moderate to severe obstructive sleep apnea (OSA) in adults with obesity When one medication can address multiple conditions, it simplifies care and reduces polypharmacy
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