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What happens when we start to account for length of time that someone is at a particular BMI, we start to tease apart the confounding variables and see evidence from this study indicating that all three sources of variation influence the health composition of BMI samples in the NHANES data and downwardly bias estimates of the BMImortality association in the US

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Curr Cardiol Rev 9 , 3354 (2013)

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Nevertheless, the precise molecular mechanisms through which microbial metabolites regulate enteroendocrine cell energy metabolism to drive GLP-1 release remain incompletely elucidated (Wang et al., 2023)