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In recent GLP-1RA trials focusing on patients with obesity, favourable effect on worsening heart failure in HFpEF patients was indicated to be modulated by baseline BMI [32], although the underlying mechanisms that explain the cardiovascular and renal benefits may not necessarily be due to weight loss alone

Austin PC (2014) The use of propensity score methods with survival or time-to-event outcomes: reporting measures of effect similar to those used in randomized experiments

The math is simple

If you are using sublingual semaglutide specifically, you might wonder whether holding medication under the tongue creates higher oral fluid concentrations that could somehow interfere with testing

Yes. In America these days, GLP-1s are as polarizing as football