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The approval is backed by data from the pivotal Phase III PERSEUS study, where treatment with subcutaneous Darzalex Faspro reduced the risk of disease progression or death by 60% in the intended patient population compared to standard of care

Foundayo (orforglipron) is a once-daily oral GLP-1 receptor agonist approved by the FDA in April 2026 for weight management in adults with obesity or overweight

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The comparison between phentermine and GLP-1 medications and the phentermine versus semaglutide comparison may also be relevant for patients exploring lower-cost pharmaceutical alternatives when GLP-1 access becomes restricted