Common side effects include frequent urination, urinary tract and genital yeast infections, increased thirst, nausea, joint pain, upper respiratory infections, increased cholesterol, and weight loss
* Internal Medicine Specialist & Medical Director Candidate At Hospitals, medical centres and polyclinic | Transforming Patient Care through Strategic Clinical Leadership | Quality & Patient Safety Expert The Era of CardiovascularKidneyMetabolic (CKM) Medicine Has Arrived Published online on 9 June 2026, the new AHA/ACC/ADA/ASN CKM Syndrome Guideline is the first comprehensive multisociety guideline to address obesity, type 2 diabetes, chronic kidney disease, and cardiovascular disease as one interconnected disease continuum
Gallbladder disease : Significant weight loss associated with GLP-1 therapies may increase the risk of gallstones
3,10 A 12-week weight-loss trial in people with RA and obesity showed improvements in disease activity in the diet group, though the between-group difference didnt reach statistical significance
These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs