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The matching variables included demographic characteristics (age and sex), physical examination findings (body mass index, blood pressure), laboratory data results (hemoglobin A1c, fasting plasma glucose, creatinine, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides and cTroponin I), comorbidities (presence of hypertension, dyslipidemia, atrial fibrillation,heart failue, smokers and diabetes duration), and concomitant medications (beta-blockers, ACEI/ARB/ARNI, SGLT2-inhibitors,statins, antiplatelet drugs,and anticoagulant drugs)

Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other pathophysiological consequences: An update on glucose toxicity