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In clinical trials, patients were sometimes allowed to stay at a lower dose for up to 8 weeks if needed to let side effects settle down

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doi:10.1016/j.mam.2008.08.006 2

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In a randomized trial of adults with obesity, those who participated in an 8-week stress management program including breathing exercises, muscle relaxation, and guided visualization lost significantly more weight than those who didnt partake in the program