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Thereafter, the animals were returned to their cages in pairs, and food and water were provided ad libitum

The first CO 2 concentration was set at 400 mol mol 1 which approached the greenhouse CO 2 concentration and increased to 2000 mol mol 1 and then successively decreased from 2000 to 0 mol mol 1

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however, its potential as an anxiolytic in humans needs to be evaluated further