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MOTS-c adds meaningful benefit at this level because cellular energy efficiency becomes a limiting factor when dietary deficit is already dialed in

This approach in exposure selection can create selection bias where those who could tolerate the drug for 30 days and potentially were not experiencing gastroparesis (the mechanism behind aspiration pneumonia) were included in the study which might be one reason the study did not find an increase in the risk of aspiration pneumonia compared with other studies

Pomegranate Health states they use FDA-regulated pharmacies, but the specific pharmacies they partner with may vary

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This highlights the importance of balance and moderation in any supplementation strategy