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The upregulation of pyoverdine biosynthesis in GSH-disrupted biofilms suggests that combining treatment with iron chelation may enhance the efficacy by preventing biofilm reformation (17, 19)

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Si bien, el diseo del estudio (ensayo clnico aleatorizado y doble ciego) permite determinar la validez de nuestros resultados, puesto que constituyen el ms alto grado de evidencia, tambin es importante considerar las limitantes, una de las cuales es no haber evaluado los niveles sricos de levocarnitina, ya que stos hubieran sido de utilidad para conocer si haba deficiencias entre los grupos al inicio del estudio y su comportamiento a lo largo de ste

The assays designated standard range was between 0.1 through to 46.0 nM